18 citations · 33 across the 6 of their papers we have counts for
6 papers
HistoWAS: A Pathomics Framework for Large-Scale Feature-Wide Association Studies of Tissue Topology and Patient Outcomes
Yuechen Yang, Junlin Guo, Yanfan Zhu +10
High-throughput "pathomic" analysis of Whole Slide Images (WSIs) offers new opportunities to study tissue characteristics and for biomarker discovery. However, the clinical relevan…
Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomas
Loan Vulliard, Teresa Glauner, Sven Truxa +8
Colorectal cancer (CRC) is highly heterogeneous, with five-year survival rates dropping from 90% in localized disease to 15% with distant metastases. Disease progressio…
ContextFlow: Context-Aware Flow Matching For Trajectory Inference From Spatial Omics Data
Santanu Subhash Rathod, Francesco Ceccarelli, Sean B. Holden +3
Inferring trajectories from longitudinal spatially-resolved omics data is fundamental to understanding the dynamics of structural and functional tissue changes in development, rege…
DOT: A flexible multi-objective optimization framework for transferring features across single-cell and spatial omics
Arezou Rahimi, Luis A. Vale-Silva, Maria Faelth Savitski +2
Single-cell RNA sequencing (scRNA-seq) and spatially-resolved imaging/sequencing technologies have revolutionized biomedical research. On one hand, scRNA-seq provides information a…
Meta-Model Framework for Surrogate-Based Parameter Estimation in Dynamical Systems
Žiga Lukšič, Jovan Tanevski, Sašo Džeroski +1
The central task in modeling complex dynamical systems is parameter estimation. This task involves numerous evaluations of a computationally expensive objective function. Surrogate…
Decoupling approximation robustly reconstructs directed dynamical networks
Nikola Simidjievski, Jovan Tanevski, Bernard Zenko +3
Methods for reconstructing the topology of complex networks from time-resolved observations of node dynamics are gaining relevance across scientific disciplines. Of biggest practic…