3 papers
physics.bio-ph2021
Energetic constraints on filament mediated cell polarization
Harmen Wierenga, Pieter Rein ten Wolde
Cell polarization underlies many cellular processes, such as differentiation, migration, and budding. Many living cells, such as budding yeast and fission yeast, use cytoskeletal s…
physics.bio-ph2019
Diffusible crosslinkers cause superexponential friction forces
Harmen Wierenga, Pieter Rein ten Wolde
The mitotic spindle lies at the heart of the spatio-temporal control over cellular components during cell division. The spindle consists of microtubules, which are not only crossli…
physics.bio-ph2018
Quantifying fluctuations in reversible enzymatic cycles and clocks
Harmen Wierenga, Pieter Rein ten Wolde, Nils B. Becker
Biochemical reactions are fundamentally noisy at a molecular scale. This limits the precision of reaction networks, but also allows fluctuation measurements which may reveal the st…