2 papers
stat.ME2019
A Bayesian Phylogenetic Hidden Markov Model for B Cell Receptor Sequence Analysis
Amrit Dhar, Duncan K. Ralph, Vladimir N. Minin +1
The human body is able to generate a diverse set of high affinity antibodies, the soluble form of B cell receptors (BCRs), that bind to and neutralize invading pathogens. The natur…
q-bio.BM2018
Predicting B Cell Receptor Substitution Profiles Using Public Repertoire Data
Amrit Dhar, Kristian Davidsen, Frederick A. Matsen +1
B cells develop high affinity receptors during the course of affinity maturation, a cyclic process of mutation and selection. At the end of affinity maturation, a number of cells s…