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q-bio.TO2021
Self-organization in embryonic development: myth and reality
Stuart A. Newman
"Self-organization" has become a watchword in developmental biology, characterizing observations in which embryonic or induced stem cells of animals replicate morphological steps a…
q-bio.TO2019
Cell differentiation: what have we learned in 50 years?
Stuart A. Newman
I revisit two theories of cell differentiation in multicellular organisms published a half-century ago, Stuart Kauffman's global gene regulatory dynamics (GGRD) model and Roy Britt…