17 citations · 26 across the 11 of their papers we have counts for
11 papers
Bidirectional human-AI collaboration in brain tumour assessments improves both expert human and AI agent performance
James K Ruffle, Samia Mohinta, Guilherme Pombo +13
The benefits of artificial intelligence (AI) human partnerships-evaluating how AI agents enhance expert human performance-are increasingly studied. Though rarely evaluated in healt…
Predicting brain tumour enhancement from non-contrast MR imaging with artificial intelligence: a multi-cohort retrospective diagnostic accuracy study
James K Ruffle, Samia Mohinta, Guilherme Pombo +13
Brain tumour MRI typically requires both pre- and post-contrast imaging, but gadolinium is not always desirable (frequent follow-up, renal impairment, allergy, paediatric patients)…
Generalizable automated ischaemic stroke lesion segmentation with vision transformers
Chris Foulon, Robert Gray, James K. Ruffle +13
Ischaemic stroke, a leading cause of death and disability, critically relies on neuroimaging for characterising the anatomical pattern of injury. Diffusion-weighted imaging (DWI) p…
Deep generative computed perfusion-deficit mapping of ischaemic stroke
Chayanin Tangwiriyasakul, Pedro Borges, Guilherme Pombo +8
Focal deficits in ischaemic stroke result from impaired perfusion downstream of a critical vascular occlusion. While parenchymal lesions are traditionally used to predict clinical…
Computational limits to the legibility of the imaged human brain
James K Ruffle, Robert J Gray, Samia Mohinta +5
Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clin…
The minimal computational substrate of fluid intelligence
Amy PK Nelson, Joe Mole, Guilherme Pombo +6
The quantification of cognitive powers rests on identifying a behavioural task that depends on them. Such dependence cannot be assured, for the powers a task invokes cannot be expe…
Deep Variational Lesion-Deficit Mapping
Guilherme Pombo, Robert Gray, Amy P. K. Nelson +3
Causal mapping of the functional organisation of the human brain requires evidence of \textit{necessity} available at adequate scale only from pathological lesions of natural origi…
Individualized prescriptive inference in ischaemic stroke
Dominic Giles, Chris Foulon, Guilherme Pombo +8
The gold standard in the treatment of ischaemic stroke is set by evidence from randomized controlled trials, based on simple descriptions of presumptively homogeneous populations.…
Brain tumour genetic network signatures of survival
James K Ruffle, Samia Mohinta, Guilherme Pombo +6
Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and…
Equitable modelling of brain imaging by counterfactual augmentation with morphologically constrained 3D deep generative models
Guilherme Pombo, Robert Gray, Jorge Cardoso +4
We describe Countersynth, a conditional generative model of diffeomorphic deformations that induce label-driven, biologically plausible changes in volumetric brain images. The mode…
Bayesian Volumetric Autoregressive generative models for better semisupervised learning
Guilherme Pombo, Robert Gray, Tom Varsavsky +2
Deep generative models are rapidly gaining traction in medical imaging. Nonetheless, most generative architectures struggle to capture the underlying probability distributions of v…