3 papers
q-bio.CB2019
Two channel compartmentalized microfluidic chip for real time monitoring of the metastatic cascade
Hilaria Mollica, Roberto Palomba, Rosita Primavera +1
Metastases are the primary cause of death in cancer patients. Small animal models are helping in dissecting some of key features in the metastatic cascade. Yet, tools for systemati…
q-bio.QM2019
Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots
Marianna Colasuonno, Anna Lisa Palange, Rachida Aid +8
Tissue plasminogen activator (tPA) is the sole approved therapeutic molecule for the treatment of acute ischemic stroke. Yet, only a small percentage of patients could benefit from…
q-bio.QM2019
Hierarchical microplates as drug depots with controlled geometry, rigidity and therapeutic efficacy
Martina Di Francesco, Rosita Primavera, Davide Romanelli +7
A variety of microparticles have been proposed for the sustained and localized delivery of drugs whit the objective of increasing therapeutic indexes by circumventing filtering org…