34 citations · 34 across the 2 of their papers we have counts for
4 papers
Two channel compartmentalized microfluidic chip for real time monitoring of the metastatic cascade
Hilaria Mollica, Roberto Palomba, Rosita Primavera +1
Metastases are the primary cause of death in cancer patients. Small animal models are helping in dissecting some of key features in the metastatic cascade. Yet, tools for systemati…
Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots
Marianna Colasuonno, Anna Lisa Palange, Rachida Aid +8
Tissue plasminogen activator (tPA) is the sole approved therapeutic molecule for the treatment of acute ischemic stroke. Yet, only a small percentage of patients could benefit from…
Deciphering the relative contribution of vascular inflammation and blood rheology in metastatic spreading
Hilaria Mollica, Alessandro Coclite, Marco E. Miali +5
Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is…
Predicting different adhesive regimens of circulating particles at blood capillary walls
A. Coclite, H. Mollica, S. Ranaldo +3
A fundamental step in the rational design of vascular targeted particles is the firm adhesion at the blood vessel walls. Here, a combined Lattice Boltzmann Immersed Boundary model…