681 citations · 957 across the 11 of their papers we have counts for
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Hyper-Molecules: on the Representation and Recovery of Dynamical Structures, with Application to Flexible Macro-Molecular Structures in Cryo-EM
Roy R. Lederman, Joakim Andén, Amit Singer
Cryo-electron microscopy (cryo-EM), the subject of the 2017 Nobel Prize in Chemistry, is a technology for determining the 3-D structure of macromolecules from many noisy 2-D projec…
APPLE Picker: Automatic Particle Picking, a Low-Effort Cryo-EM Framework
Ayelet Heimowitz, Joakim Andén, Amit Singer
Particle picking is a crucial first step in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM). Selecting particles from the micrographs is difficult…
Covariance estimation using conjugate gradient for 3D classification in Cryo-EM
Joakim Andén, Eugene Katsevich, Amit Singer
Classifying structural variability in noisy projections of biological macromolecules is a central problem in Cryo-EM. In this work, we build on a previous method for estimating the…