3 papers
stat.ME2026
A Quasi-Regression Method for the Mediation Analysis of Zero-Inflated Single-Cell Data
Seungjun Ahn, Donald Porchia, Panos Roussos +3
Recent advances in single-cell technologies have advanced our understanding of gene regulation and cellular heterogeneity at single-cell resolution. Single-cell data contain both g…
stat.ME2025
A Statistical Framework for Co-Mediators of Zero-Inflated Single-Cell RNA-Seq Data
Seungjun Ahn, Li Chen, Maaike van Gerwen +2
Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of cellular heterogeneity, enabling detailed molecular profiling at the individual cell level. However, integrat…
q-bio.GN2019
Transcriptomic Causal Networks identified patterns of differential gene regulation in human brain from Schizophrenia cases versus controls
Akram Yazdani, Raul Mendez-Giraldez, Michael R Kosorok +1
Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, which work in a coordinated way. However, the vast majority of stu…