93 citations · 99 across the 4 of their papers we have counts for
4 papers
tttrlib: modular software for integrating fluorescence spectroscopy, imaging, and molecular modeling
Thomas-Otavio Peulen, Katherina Hemmen, Annemarie Greife +6
We introduce software for reading, writing and processing fluorescence single-molecule and image spectroscopy data and developing analysis pipelines that unifies various spectrosco…
Automated and optimally FRET-assisted structural modeling
Mykola Dimura, Thomas O. Peulen, Hugo Sanabria +4
FRET experiments can yield state-specific structural information on complex dynamic biomolecular assemblies. However, FRET experiments need to be combined with computer simulations…
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
Maksym Tsytlonok, Hugo Sanabria, Yuefeng Wang +12
p27 (p27) is an intrinsically disordered protein (IDP) that folds upon binding to cyclin-dependent kinase (Cdk)cyclin complexes (e.g., Cdk2cyclin A), inhibiting thei…
Resolving dynamics and function of transient states in single enzyme molecules
Hugo Sanabria, Dmitro Rodnin, Katherina Hemmen +9
We used a hybrid fluorescence spectroscopic toolkit to monitor T4 Lysozyme (T4L) in action. By unraveling the kinetic and dynamic interplay of the conformational states, we sought…