2 papers
stat.CO2019
Bayesian models for survival data of clinical trials: Comparison of implementations using R software
Lucie Biard, Anne Bergeron, Sylvie Chevret
Objective: To provide guidance for the use of the main functions available in R for performing post hoc Bayesian analysis of a randomized clinical trial with a survival endpoint us…
stat.AP2019
A simulation study of methods for handling disease progression in dose-finding clinical trials
Lucie Biard, Bin Cheng, Gulam A. Manji +1
In traditional dose-finding studies, dose-limiting toxicity (DLT) is determined within a fixed time observation window where DLT is often defined as a binary outcome. In the settin…