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q-bio.GN2023
Scalable telomere-to-telomere assembly for diploid and polyploid genomes with double graph
Haoyu Cheng, Mobin Asri, Julian Lucas +2
Despite recent advances in the length and the accuracy of long-read data, building haplotype-resolved genome assemblies from telomere to telomere still requires considerable comput…
q-bio.GN2023★ 1 cited
De novo reconstruction of satellite repeat units from sequence data
Yujie Zhang, Justin Chu, Haoyu Cheng +1
Satellite DNA are long tandemly repeating sequences in a genome and may be organized as high-order repeats (HORs). They are enriched in centromeres and are challenging to assemble.…