32 citations · 33 across the 4 of their papers we have counts for
5 papers
Distributed online estimation of biophysical neural networks
Thiago B. Burghi, Timothy O'Leary, Rodolphe Sepulchre
In this work, we propose a distributed adaptive observer for a class of nonlinear networked systems inspired by biophysical neural network models. Neural systems learn by adjusting…
Global and local synaptic regulation determine the stability of homeostatic plasticity
Saeed Aljaberi, Adriano Bellotti, Timothy O'Leary +1
Neurons regulate the distribution of signaling components across an extended tree-like cellular structure using both local and global feedback control. This is hypothesized to allo…
Dendritic trafficking: synaptic scaling and structural plasticity
Saeed Aljaberi, Timothy O'Leary, Fulvio Forni
Neuronal circuits internally regulate electrical signaling via a host of homeostatic mechanisms. Two prominent mechanisms, synaptic scaling and structural plasticity, are believed…
Qualitative behavior and robustness of dendritic trafficking
Saeed Aljaberi, Timothy O'Leary, Fulvio Forni
The paper studies homeostatic ion channel trafficking in neurons. We derive a nonlinear closed-loop model that captures active transport with degradation, channel insertion, averag…
Fundamental bounds on learning performance in neural circuits
Dhruva V Raman, Timothy O'Leary
How does the size of a neural circuit influence its learning performance? Intuitively, we expect the learning capacity of a neural circuit to grow with the number of neurons and sy…