activity
20172023
most citedThe impact of epilepsy surgery on the structural connectome and its relation to outcome

155 citations · 211 across the 10 of their papers we have counts for

collaborators

10 papers

q-bio.NC2023

Identifying epileptogenic abnormality by decomposing intracranial EEG and MEG power spectra

Csaba Kozma, Gabrielle Schroeder, Tom Owen +6

Identifying abnormal electroencephalographic activity is crucial in diagnosis and treatment of epilepsy. Recent studies showed that decomposing brain activity into periodic (oscill…

q-bio.NC2023

Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo

Christopher Thornton, Mariella Panagiotopoulou, Fahmida A Chowdhury +10

Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expressio…

q-bio.NC2023

Interictal MEG abnormalities to guide intracranial electrode implantation and predict surgical outcome

Thomas W. Owen, Vytene Janiukstyte, Gerard R. Hall +9

Intracranial EEG (iEEG) is the gold standard technique for epileptogenic zone (EZ) localisation, but requires a hypothesis of which tissue is epileptogenic, guided by qualitative a…

q-bio.NC2023

Identifying epileptogenic abnormalities through spatial clustering of MEG interictal band power

Thomas W. Owen, Vytene Janiukstyte, Gerard R. Hall +8

Successful epilepsy surgery depends on localising and resecting cerebral abnormalities and networks that generate seizures. Abnormalities, however, may be widely distributed across…

q-bio.NC2023★ 3 cited

Complementary structural and functional abnormalities to localise epileptogenic tissue

Jonathan J Horsley, Rhys H Thomas, Fahmida A Chowdhury +10

When investigating suitability for surgery, people with drug-refractory focal epilepsy may have intracranial EEG (iEEG) electrodes implanted to localise seizure onset. Diffusion-we…

q-bio.NC2022★ 1 cited

MEG abnormalities and mechanisms of surgical failure in neocortical epilepsy

Thomas W. Owen, Gabrielle M. Schroeder, Vytene Janiukstyte +8

Neocortical epilepsy surgery fails to achieve post-operative seizure freedom in 30-40% of cases. It is not fully understood why surgery in some patients is unsuccessful. Comparing…

q-bio.NC2022★ 6 cited

Intracranial EEG structure-function coupling predicts surgical outcomes in focal epilepsy

Nishant Sinha, John S. Duncan, Beate Diehl +9

Alterations to structural and functional brain networks have been reported across many neurological conditions. However, the relationship between structure and function -- their co…

q-bio.NC2021★ 2 cited

Normative brain mapping of interictal intracranial EEG to localise epileptogenic tissue

Peter N Taylor, Christoforos A Papasavvas, Thomas W Owen +11

The identification of abnormal electrographic activity is important in a wide range of neurological disorders, including epilepsy for localising epileptogenic tissue. However, this…

q-bio.NC2019★ 44 cited

Interictal intracranial EEG for predicting surgical success: the importance of space and time

Yujiang Wang, Nishant Sinha, Gabrielle M. Schroeder +8

Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challe…

q-bio.NC2017★ 155 cited

The impact of epilepsy surgery on the structural connectome and its relation to outcome

Peter N Taylor, Nishant Sinha, Yujiang Wang +6

Temporal lobe surgical resection brings seizure remission in up to 80% of patients, with long-term complete seizure freedom in 41%. However, it is unclear how surgery impacts on th…