44 citations · 71 across the 18 of their papers we have counts for
18 papers
Seizure duration is associated with multiple timescales in interictal iEEG band power
Mariella Panagiotopoulou, Gabrielle M. Schroeder, Jess Blickwedel +12
Background Seizure severity can change from one seizure to the next within individual people with epilepsy. It is unclear if and how seizure severity is modulated over longer times…
From Bedside to Desktop: A Data Protocol for Normative Intracranial EEG and Abnormality Mapping
Heather Woodhouse, Sarah J. Gascoigne, Gerard Hall +5
Normative mapping is a framework used to map population-level features of health-related variables. It is widely used in neuroscience research, but the literature lacks established…
Anti-seizure medication load is not correlated with early termination of seizure spread
Nathan Evans, Sarah J. Gascoigne, Guillermo M. Besne +11
Objective: Anti-seizure medications (ASMs) are the mainstay of treatment for epilepsy, yet their effect on seizure spread is not fully understood. Higher ASM doses have been associ…
Multi-centre normative brain mapping of intracranial EEG lifespan patterns in the human brain
Heather Woodhouse, Gerard Hall, Callum Simpson +18
Background: Understanding healthy human brain function is crucial to identify and map pathological tissue within it. Whilst previous studies have mapped intracranial EEG (icEEG) fr…
Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes
Sarah J. Gascoigne, Nathan Evans, Gerard Hall +16
Delineation of seizure onset regions from EEG is important for effective surgical workup. However, it is unknown if their complete resection is required for seizure freedom, or in…
Identifying epileptogenic abnormality by decomposing intracranial EEG and MEG power spectra
Csaba Kozma, Gabrielle Schroeder, Tom Owen +6
Identifying abnormal electroencephalographic activity is crucial in diagnosis and treatment of epilepsy. Recent studies showed that decomposing brain activity into periodic (oscill…
Temporal stability of intracranial EEG abnormality maps for localising epileptogenic tissue
Yujiang Wang, Gabrielle M Schroeder, Jonathan J Horsley +8
Objective: Identifying abnormalities in interictal intracranial EEG, by comparing patient data to a normative map, has shown promise for the localisation of epileptogenic tissue an…
MEG abnormalities and mechanisms of surgical failure in neocortical epilepsy
Thomas W. Owen, Gabrielle M. Schroeder, Vytene Janiukstyte +8
Neocortical epilepsy surgery fails to achieve post-operative seizure freedom in 30-40% of cases. It is not fully understood why surgery in some patients is unsuccessful. Comparing…
A library of quantitative markers of seizure severity
Sarah J. Gascoigne, Leonard Waldmann, Mariella Panagiotopoulou +16
Purpose: Understanding fluctuations of seizure severity within individuals is important for defining treatment outcomes and response to therapy, as well as developing novel treatme…
Volumetric and structural connectivity abnormalities co-localise in TLE
Jonathan J. Horsley, Gabrielle M. Schroeder, Rhys H. Thomas +6
Patients with temporal lobe epilepsy (TLE) exhibit both volumetric and structural connectivity abnormalities relative to healthy controls. How these abnormalities inter-relate and…
Chronic iEEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states
Gabrielle M. Schroeder, Philippa J. Karoly, Matias Maturana +4
Background and Objectives: Many biological processes are modulated by rhythms on circadian and multidien timescales. In focal epilepsy, various seizure features, such as spread and…
Seizure pathways and seizure durations can vary independently within individual patients with focal epilepsy
Gabrielle M. Schroeder, Fahmida A. Chowdhury, Mark J. Cook +5
A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also termed dynamical "pathway" and the time it takes to complete that pathway, which results…
Normative brain mapping of interictal intracranial EEG to localise epileptogenic tissue
Peter N Taylor, Christoforos A Papasavvas, Thomas W Owen +11
The identification of abnormal electrographic activity is important in a wide range of neurological disorders, including epilepsy for localising epileptogenic tissue. However, this…
Fluctuations in EEG band power at subject-specific timescales over minutes to days explain changes in seizure evolutions
Mariella Panagiotopoulou, Christoforos A Papasavvas, Gabrielle M Schroeder +3
Epilepsy is recognised as a dynamic disease, where both seizure susceptibility and seizure characteristics themselves change over time. Specifically, we recently quantified the var…
Focal to bilateral tonic-clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy
Nishant Sinha, Natalie Peternell, Gabrielle M. Schroeder +6
Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from…
Band power modulation through intracranial EEG stimulation and its cross-session consistency
Christoforos A Papasavvas, Gabrielle M Schroeder, Beate Diehl +3
Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is…
Interictal intracranial EEG for predicting surgical success: the importance of space and time
Yujiang Wang, Nishant Sinha, Gabrielle M. Schroeder +8
Predicting post-operative seizure freedom using functional correlation networks derived from interictal intracranial EEG has shown some success. However, there are important challe…
Personalised network modelling in epilepsy
Yujiang Wang, Gabrielle Marie Schroeder, Nishant Sinha +1
Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating…