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q-bio.QM2019
Reconstructing continuous distributions of 3D protein structure from cryo-EM images
Ellen D. Zhong, Tristan Bepler, Joseph H. Davis +1
Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structure of proteins and other macromolecular complexes at near-atomic resolution. In single particl…
q-bio.QM2018
Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs
Tristan Bepler, Andrew Morin, Julia Brasch +3
Cryo-electron microscopy (cryoEM) is an increasingly popular method for protein structure determination. However, identifying a sufficient number of particles for analysis (often >…