2 papers
stat.AP2019
Developing Biomarker Combinations in Multicenter Studies via Direct Maximization and Penalization
Allison Meisner, Chirag R. Parikh, Kathleen F. Kerr
Motivated by a study of acute kidney injury, we consider the setting of biomarker studies involving patients at multiple centers where the goal is to develop a biomarker combinatio…
stat.ME2019
Combining Biomarkers by Maximizing the True Positive Rate for a Fixed False Positive Rate
Allison Meisner, Marco Carone, Margaret S. Pepe +1
Biomarkers abound in many areas of clinical research, and often investigators are interested in combining them for diagnosis, prognosis, or screening. In many applications, the tru…