5 papers
Mixed Ion Beams Enable Simultaneous Treatment and Real-Time Imaging in Carbon Ion Therapy
Lennart Volz, Ronja Hetzel, Maximilian Dick +19
Carbon ion therapy is one of the most advanced forms of radiotherapy, promising improved efficacy against resistant cancers. However, the high precision offered by the carbon ion B…
Pan-Cancer mitotic figures detection and domain generalization: MIDOG 2025 Challenge
Zhuoyan Shen, Esther Bär, Maria Hawkins +2
This report details our submission to the Mitotic Domain Generalization (MIDOG) 2025 challenge, which addresses the critical task of mitotic figure detection in histopathology for…
OMG-Net: A Deep Learning Framework Deploying Segment Anything to Detect Pan-Cancer Mitotic Figures from Haematoxylin and Eosin-Stained Slides
Zhuoyan Shen, Mikael Simard, Douglas Brand +14
Mitotic activity is an important feature for grading several cancer types. Counting mitotic figures (MFs) is a time-consuming, laborious task prone to inter-observer variation. Ina…
Immunocto: a massive immune cell database auto-generated for histopathology
Mikaël Simard, Zhuoyan Shen, Konstantin Bräutigam +3
With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potent…
Optimal particle type and projection number in multi-modality relative stopping power acquisition
Marta F. Dias, Charles-Antoine Collins-Fekete, Lennart Volz +3
Proton radiography combined with X-ray computed tomography (CT) has been proposed to obtain a patient-specific calibration curve and reduce range uncertainties in cancer treatment…