89 citations · 89 across the 2 of their papers we have counts for
2 papers
q-bio.QM2019
Topological constraints in eukaryotic genomes and how they can be exploited to improve spatial models of chromosomes
Angelo Rosa, Marco Di Stefano, Cristian Micheletti
Several orders of magnitude typically separate the contour length of eukaryotic chromosomes and the size of the nucleus where they are confined. The ensuing topological constraints…
physics.bio-ph2016★ 89 cited
Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
Marco Di Stefano, Jonas Paulsen, Tonje G. Lien +2
Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we…