activity
20152025
most citedA computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation

91 citations · 351 across the 10 of their papers we have counts for

collaborators

11 papers

physics.med-ph2025

Non-Intrusive Parametrized-Background Data-Weak Reconstruction of Cardiac Displacement Fields from Sparse MRI-like Observations

Francesco C. Mantegazza, Federica Caforio, Christoph Augustin +3

Personalized cardiac diagnostics require accurate reconstruction of myocardial displacement fields from sparse clinical imaging data, yet current methods often demand intrusive acc…

cs.LG2025

Physics-informed neural network estimation of active material properties in time-dependent cardiac biomechanical models

Matthias Höfler, Francesco Regazzoni, Stefano Pagani +5

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical…

cs.LG2023★ 60 cited

Physics-informed Neural Network Estimation of Material Properties in Soft Tissue Nonlinear Biomechanical Models

Federica Caforio, Francesco Regazzoni, Stefano Pagani +5

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the in…

physics.flu-dyn2021★ 54 cited

Global Sensitivity Analysis of Four Chamber Heart Hemodynamics Using Surrogate Models

Elias Karabelas, Stefano Longobardi, Jana Fuchsberger +7

Computational Fluid Dynamics (CFD) is used to assist in designing artificial valves and planning procedures, focusing on local flow features. However, assessing the impact on overa…

math.NA2021★ 26 cited

An accurate, robust, and efficient finite element framework for anisotropic, nearly and fully incompressible elasticity

Elias Karabelas, Matthias A. F. Gsell, Gundolf Haase +2

Fiber-reinforced soft biological tissues are typically modeled as hyperelastic, anisotropic, and nearly incompressible materials. To enforce incompressibility a multiplicative spli…

q-bio.TO2020★ 91 cited

A computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation

Christoph M. Augustin, Matthias A. F. Gsell, Elias Karabelas +5

Computer models of cardiac electro-mechanics (EM) show promise as an effective means for quantitative analysis of clinical data and, potentially, for predicting therapeutic respons…