activity
20152025
most citedA computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation

91 citations · 351 across the 10 of their papers we have counts for

collaborators

11 papers

physics.med-ph2025

Non-Intrusive Parametrized-Background Data-Weak Reconstruction of Cardiac Displacement Fields from Sparse MRI-like Observations

Francesco C. Mantegazza, Federica Caforio, Christoph Augustin +3

Personalized cardiac diagnostics require accurate reconstruction of myocardial displacement fields from sparse clinical imaging data, yet current methods often demand intrusive acc…

cs.LG2025

Physics-informed neural network estimation of active material properties in time-dependent cardiac biomechanical models

Matthias Höfler, Francesco Regazzoni, Stefano Pagani +5

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical…

cs.LG2023★ 60 cited

Physics-informed Neural Network Estimation of Material Properties in Soft Tissue Nonlinear Biomechanical Models

Federica Caforio, Francesco Regazzoni, Stefano Pagani +5

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the in…

physics.flu-dyn2021★ 54 cited

Global Sensitivity Analysis of Four Chamber Heart Hemodynamics Using Surrogate Models

Elias Karabelas, Stefano Longobardi, Jana Fuchsberger +7

Computational Fluid Dynamics (CFD) is used to assist in designing artificial valves and planning procedures, focusing on local flow features. However, assessing the impact on overa…

math.NA2021★ 26 cited

An accurate, robust, and efficient finite element framework for anisotropic, nearly and fully incompressible elasticity

Elias Karabelas, Matthias A. F. Gsell, Gundolf Haase +2

Fiber-reinforced soft biological tissues are typically modeled as hyperelastic, anisotropic, and nearly incompressible materials. To enforce incompressibility a multiplicative spli…

q-bio.TO2020★ 91 cited

A computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation

Christoph M. Augustin, Matthias A. F. Gsell, Elias Karabelas +5

Computer models of cardiac electro-mechanics (EM) show promise as an effective means for quantitative analysis of clinical data and, potentially, for predicting therapeutic respons…

physics.flu-dyn2020★ 3 cited

On the Incorporation of Obstacles in a Fluid Flow Problem Using a Navier-Stokes-Brinkman Penalization Approach

Jana Fuchsberger, Elias Karabelas, Philipp Aigner +4

Simulating the interaction of fluids with immersed moving solids is playing an important role for gaining a better quantitative understanding of how fluid dynamics is altered by th…

physics.app-ph2019★ 28 cited

Versatile stabilized finite element formulations for nearly and fully incompressible solid mechanics

Elias Karabelas, Gundolf Haase, Gernot Plank +1

Computational formulations for large strain, polyconvex, nearly incompressible elasticity have been extensively studied, but research on enhancing solution schemes that offer bette…

physics.med-ph2019★ 41 cited

Towards a Computational Framework for Modeling the Impact of Aortic Coarctations upon Left Ventricular Load

Elias Karabelas, Matthias A. F. Gsell, Christoph M. Augustin +6

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation…

physics.med-ph2019★ 28 cited

Assessment of wall stresses and mechanical heart power in the left ventricle: Finite element modeling versus Laplace analysis

Matthias A. F. Gsell, Christoph M. Augustin, Anton J. Prassl +6

Introduction: Stenotic aortic valve disease (AS) causes pressure overload of the left ventricle (LV) that may trigger adverse remodeling and precipitate progression towards heart f…

math.NA2015★ 20 cited

Generating admissible space-time meshes for moving domains in -dimensions

Elias Karabelas, Martin Neumüller

In this paper we present a discontinuous Galerkin finite element method for the solution of the transient Stokes equations on moving domains. For the discretization we use an inter…