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stat.AP2022
Using Targeted Maximum Likelihood Estimation to Estimate Treatment Effect with Longitudinal Continuous or Binary Data: A Systematic Evaluation of 28 Diabetes Clinical Trials
Lingjing Jiang, Michael Rosenblum, Yu Du
The primary analysis of clinical trials in diabetes therapeutic area often involves a mixed-model repeated measure (MMRM) approach to estimate the average treatment effect for long…
stat.AP2014★ 4 cited
interAdapt -- An Interactive Tool for Designing and Evaluating Randomized Trials with Adaptive Enrollment Criteria
Aaron Fisher, Harris Jaffee, Michael Rosenblum
The interAdapt R package is designed to be used by statisticians and clinical investigators to plan randomized trials. It can be used to determine if certain adaptive designs offer…