6 papers
Bayesian uncertainty quantification for micro-swimmers with fully resolved hydrodynamics
Karen Larson, Sarah Olson, Anastasios Matzavinos
Due to the computational complexity of micro-swimmer models with fully resolved hydrodynamics, parameter estimation has been prohibitively expensive. Here, we describe a Bayesian u…
Computational framework to capture the spatiotemporal density of cells with a cumulative environmental coupling
Michael A. Yereniuk, Sarah D. Olson
Stochastic agent-based models can account for millions of cells with spatiotemporal movement that can be a function of different factors. However, these simulations can be computat…
A hybrid cellular automaton model of cartilage regeneration capturing the interactions between cellular dynamics and scaffold porosity
Simone Cassani, Sarah D. Olson
To accelerate the development of strategies for cartilage tissue engineering, models are necessary to study the interactions between cellular dynamics and scaffold (SC) porosity. I…
Global Density Analysis for an Off-Lattice Agent-Based Model
Michael A. Yereniuk, Sarah D. Olson
Agent-based (AB) or Cellular Automata (CA) models are rule based and are a relatively simple discrete method that can be used to simulate complex interactions of many agents or cel…
A 3-dimensional model of flagellar swimming in a Brinkman fluid
Nguyenho Ho, Karin Leiderman, Sarah Olson
We investigate 3-dimensional flagellar swimming in a fluid with a sparse network of stationary obstacles or fibers. The Brinkman equation is used to model the average fluid flow wh…
Emergent three-dimensional sperm motility: Coupling calcium dynamics and preferred curvature in a Kirchhoff rod model
Lucia Carichino, Sarah D. Olson
Changes in calcium concentration along the sperm flagellum regulate sperm motility and hyperactivation, characterized by an increased flagellar bend amplitude and beat asymmetry, e…