activity
20192025
most citedMultilevel and multifidelity uncertainty quantification for cardiovascular hemodynamics

105 citations · 152 across the 16 of their papers we have counts for

collaborators

21 papers

cs.LG2025

Assessing the performance of correlation-based multi-fidelity neural emulators

Cristian J. Villatoro, Gianluca Geraci, Daniele E. Schiavazzi

Outer loop tasks such as optimization, uncertainty quantification or inference can easily become intractable when the underlying high-fidelity model is computationally expensive. S…

stat.ML2025

On the performance of multi-fidelity and reduced-dimensional neural emulators for inference of physiological boundary conditions

Chloe H. Choi, Andrea Zanoni, Daniele E. Schiavazzi +1

Solving inverse problems in cardiovascular modeling is particularly challenging due to the high computational cost of running high-fidelity simulations. In this work, we focus on B…

math.NA2025

Enabling stratified sampling in high dimensions via nonlinear dimensionality reduction

Gianluca Geraci, Daniele E. Schiavazzi, Andrea Zanoni

We consider the problem of propagating the uncertainty from a possibly large number of random inputs through a computationally expensive model. Stratified sampling is a well-known…

cs.LG2025

Rule-based and reinforcement-learning policies for resource allocation in a pediatric echo lab: a simulation study

Bozhi Sun, Seda Tierney, Jeffrey A. Feinstein +3

Scheduling echocardiographic examinations in a hospital setting presents significant challenges due to non-deterministic factors such as patient no-shows, variable arrival times, a…

physics.flu-dyn2024

Personalized and uncertainty-aware coronary hemodynamics simulations: From Bayesian estimation to improved multi-fidelity uncertainty quantification

Karthik Menon, Andrea Zanoni, Owais Khan +4

Simulations of coronary hemodynamics have improved non-invasive clinical risk stratification and treatment outcomes for coronary artery disease, compared to relying on anatomical i…

math.NA2024

InVAErt networks for amortized inference and identifiability analysis of lumped parameter hemodynamic models

Guoxiang Grayson Tong, Carlos A. Sing Long, Daniele E. Schiavazzi

Estimation of cardiovascular model parameters from electronic health records (EHR) poses a significant challenge primarily due to lack of identifiability. Structural non-identifiab…

cs.LG2024

Quantification of total uncertainty in the physics-informed reconstruction of CVSim-6 physiology

Mario De Florio, Zongren Zou, Daniele E. Schiavazzi +1

When predicting physical phenomena through simulation, quantification of the total uncertainty due to multiple sources is as crucial as making sure the underlying numerical model i…

math.NA2024★ 3 cited

Neural active manifolds: nonlinear dimensionality reduction for uncertainty quantification

Andrea Zanoni, Gianluca Geraci, Matteo Salvador +2

We present a new approach for nonlinear dimensionality reduction, specifically designed for computationally expensive mathematical models. We leverage autoencoders to discover a on…

cs.CE2024★ 2 cited

Bayesian Windkessel calibration using optimized 0D surrogate models

Jakob Richter, Jonas Nitzler, Luca Pegolotti +6

Boundary condition (BC) calibration to assimilate clinical measurements is an essential step in any subject-specific simulation of cardiovascular fluid dynamics. Bayesian calibrati…

stat.AP2024

Global sensitivity analysis with multifidelity Monte Carlo and polynomial chaos expansion for carotid artery haemodynamics

Friederike Schäfer, Daniele E. Schiavazzi, Leif Rune Hellevik +1

Computational models of the cardiovascular system are increasingly used for the diagnosis, treatment, and prevention of cardiovascular disease. Before being used for translational…

stat.ME2023★ 1 cited

Improved multifidelity Monte Carlo estimators based on normalizing flows and dimensionality reduction techniques

Andrea Zanoni, Gianluca Geraci, Matteo Salvador +3

We study the problem of multifidelity uncertainty propagation for computationally expensive models. In particular, we consider the general setting where the high-fidelity and low-f…

physics.med-ph2023

A Probabilistic Neural Twin for Treatment Planning in Peripheral Pulmonary Artery Stenosis

John D. Lee, Jakob Richter, Martin R. Pfaller +8

The substantial computational cost of high-fidelity models in numerical hemodynamics has, so far, relegated their use mainly to offline treatment planning. New breakthroughs in dat…

cs.LG2023

InVAErt networks: a data-driven framework for model synthesis and identifiability analysis

Guoxiang Grayson Tong, Carlos A. Sing Long, Daniele E. Schiavazzi

Use of generative models and deep learning for physics-based systems is currently dominated by the task of emulation. However, the remarkable flexibility offered by data-driven arc…

cs.DC2022

Data-driven synchronization-avoiding algorithms in the explicit distributed structural analysis of soft tissue

Guoxiang Grayson Tong, Daniele E. Schiavazzi

We propose a data-driven framework to increase the computational efficiency of the explicit finite element method in the structural analysis of soft tissue. An encoder-decoder long…

cs.LG2022

Multifidelity data fusion in convolutional encoder/decoder networks

Lauren Partin, Gianluca Geraci, Ahmad Rushdi +2

We analyze the regression accuracy of convolutional neural networks assembled from encoders, decoders and skip connections and trained with multifidelity data. Besides requiring si…

eess.IV2022

An analysis of reconstruction noise from undersampled 4D flow MRI

Lauren Partin, Daniele E. Schiavazzi, Carlos A. Sing Long

Novel Magnetic Resonance (MR) imaging modalities can quantify hemodynamics but require long acquisition times, precluding its widespread use for early diagnosis of cardiovascular d…

q-bio.QM2020★ 34 cited

Geometric Uncertainty in Patient-Specific Cardiovascular Modeling with Convolutional Dropout Networks

Gabriel Maher, Casey Fleeter, Daniele Schiavazzi +1

We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional…

physics.med-ph2019★ 2 cited

Multi-fidelity estimators for coronary circulation models under clinically-informed data uncertainty

Jongmin Seo, Casey Fleeter, Andrew M. Kahn +2

Numerical models are increasingly used for non-invasive diagnosis and treatment planning in coronary artery disease, where service-based technologies have proven successful in iden…

physics.med-ph2019★ 5 cited

The effects of clinically-derived parametric data uncertainty in patient-specific coronary simulations with deformable walls

Jongmin Seo, Daniele E. Schiavazzi, Andrew M. Kahn +1

Cardiovascular simulations are increasingly used for non-invasive diagnosis of cardiovascular disease, to guide treatment decisions, and in the design of medical devices. Quantitat…

q-bio.QM2019★ 105 cited

Multilevel and multifidelity uncertainty quantification for cardiovascular hemodynamics

Casey M. Fleeter, Gianluca Geraci, Daniele E. Schiavazzi +2

Standard approaches for uncertainty quantification in cardiovascular modeling pose challenges due to the large number of uncertain inputs and the significant computational cost of…

physics.comp-ph2019

Performance of preconditioned iterative linear solvers for cardiovascular simulations in rigid and deformable vessels

Jongmin Seo, Daniele E. Schiavazzi, Alison L. Marsden

Computing the solution of linear systems of equations is invariably the most time consuming task in the numerical solutions of PDEs in many fields of computational science. In this…