261 citations · 1.1k across the 9 of their papers we have counts for
Showing 2015Show all
2 papers · 1 filter
q-bio.GN2015★ 41 cited
repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data
Yuval Elhanati, Quentin Marcou, Thierry Mora +1
The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are compo…
q-bio.PE2015★ 215 cited
Inferring processes underlying B-cell repertoire diversity
Yuval Elhanati, Zachary Sethna, Quentin Marcou +3
We quantify the VDJ recombination and somatic hypermutation processes in human B-cells using probabilistic inference methods on high-throughput DNA sequence repertoires of human B-…