181 citations · 874 across the 16 of their papers we have counts for
16 papers
Linear Viscoelastic Response of the Vertex Model with Internal and External Dissipation: Normal Modes Analysis
Sijie Tong, Rastko Sknepnek, Andrej Kosmrlj
We use the normal mode formalism to study the shear rheology of the vertex model for epithelial tissue mechanics in the overdamped linear response regime. We consider systems with…
Liquid demixing in elastic networks: cavitation, permeation, or size selection?
Pierre Ronceray, Sheng Mao, Andrej Košmrlj +1
Demixing of multicomponent biomolecular systems via liquid-liquid phase separation (LLPS) has emerged as a potentially unifying mechanism governing the formation of several membran…
Linear Viscoelastic Properties of the Vertex Model for Epithelial Tissues
Sijie Tong, Navreeta K. Singh, Rastko Sknepnek +1
Epithelial tissues act as barriers and, therefore, must repair themselves, respond to environmental changes and grow without compromising their integrity. Consequently, they exhibi…
Buckling of thermalized elastic sheets
Ali Morshedifard, Miguel Ruiz-Garcia, Mohammad Javad Abdolhosseini Qomi +1
Steady progress in the miniaturization of structures and devices has reached a scale where thermal fluctuations become relevant and it is thus important to understand how such fluc…
Method of image charges for describing linear deformation of bounded 2D solid structures with circular holes and inclusions
Siddhartha Sarkar, Matjaz Cebron, Miha Brojan +1
We present a method for predicting the linear response deformation of finite and semi-infinite 2D solid structures with circular holes and inclusions by employing the analogies wit…
Finite Temperature Phase Behavior of Viral Capsids as Oriented Particle Shells
Amit Rajnarayan Singh, Andrej Košmrlj, Robijn F. Bruinsma
A general phase-plot is proposed for discrete particle shells that allows for thermal fluctuations of the shell geometry and of the inter-particle connectivities. The phase plot co…
Non-uniform growth and surface friction determine bacterial biofilm morphology on soft substrates
Chenyi Fei, Sheng Mao, Jing Yan +5
During development, organisms acquire three-dimensional shapes with important physiological consequences. While the basic mechanisms underlying morphogenesis are known in eukaryote…
Phase behavior and morphology of multicomponent liquid mixtures
Sheng Mao, Derek Kuldinow, Mikko P. Haataja +1
Multicomponent systems are ubiquitous in nature and industry. While the physics of few-component liquid mixtures (i.e., binary and ternary ones) is well-understood and routinely ta…
Non-Hookean statistical mechanics of clamped graphene ribbons
Mark J. Bowick, Andrej Kosmrlj, David R. Nelson +1
Thermally fluctuating sheets and ribbons provide an intriguing forum in which to investigate strong violations of Hooke's Law: large distance elastic parameters are in fact not con…
Statistical mechanics of thin spherical shells
Andrej Kosmrlj, David R. Nelson
We explore how thermal fluctuations affect the mechanics of thin amorphous spherical shells. In flat membranes with a shear modulus, thermal fluctuations increase the bending rigid…
Response of thermalized ribbons to pulling and bending
Andrej Kosmrlj, David R. Nelson
Motivated by recent free-standing graphene experiments, we show how thermal fluctuations affect the mechanical properties of microscopically thin solid ribbons. A renormalization g…
Glucagon stop-go kinetics supports a monomer-trimer fibrillation model
Andrej Kosmrlj, Pia Cordsen, Anders Kyrsting +3
We investigate in vitro fibrillation kinetics of the hormone peptide glucagon at various concentrations using confocal microscopy and determine the glucagon fibril persistence leng…
Thermal Excitations of Warped Membranes
Andrej Kosmrlj, David R. Nelson
We explore thermal fluctuations of thin planar membranes with a frozen spatially-varying background metric and a shear modulus. We focus on a special class of -dimensional ``war…
Mechanical Properties of Warped Membranes
Andrej Kosmrlj, David R. Nelson
We explore how a frozen background metric affects the mechanical properties of planar membranes with a shear modulus. We focus on a special class of "warped membranes" with a prefe…
The influence of T cell development on pathogen specificity and autoreactivity
Andrej Kosmrlj, Mehran Kardar, Arup K. Chakraborty
T cells orchestrate adaptive immune responses upon activation. T cell activation requires sufficiently strong binding of T cell receptors on their surface to short peptides derived…
Thymic selection of T-cell receptors as an extreme value problem
Andrej Kosmrlj, Arup K. Chakraborty, Mehran Kardar +1
T lymphocytes (T cells) orchestrate adaptive immune responses upon activation. T cell activation requires sufficiently strong binding of T cell receptors (TCRs) on their surface to…