4 papers
Group Invariant Spectral Embedding
Yeari Vigder, Paulina Hoyos, David Thong +3
Spectral embedding methods are widely used for dimensionality reduction and clustering of high-dimensional datasets with intrinsic low-dimensional structures. Although many dataset…
Multiscale reconstruction of protein conformations from cryo-EM images
David Y. W. Thong, Ozan Öktem, Joakim Andén
We present a novel multiscale algorithm for directly recovering the atomic model structure of a protein from single-particle cryo-EM data. Our algorithm is able to estimate protein…
Do Bayesian imaging methods report trustworthy probabilities?
David Y. W. Thong, Charlesquin Kemajou Mbakam, Marcelo Pereyra
Bayesian statistics is a cornerstone of imaging sciences, underpinning many and varied approaches from Markov random fields to score-based denoising diffusion models. In addition t…
Latent likelihood ratio tests for assessing spatial kernels in epidemic models
David Thong, George Streftaris, Gavin J. Gibson
One of the most important issues in the critical assessment of spatio-temporal stochastic models for epidemics is the selection of the transmission kernel used to represent the rel…