566 citations · 716 across the 21 of their papers we have counts for
7 papers · 1 filter
Incorporating Pre-training Paradigm for Antibody Sequence-Structure Co-design
Kaiyuan Gao, Lijun Wu, Jinhua Zhu +8
Antibodies are versatile proteins that can bind to pathogens and provide effective protection for human body. Recently, deep learning-based computational antibody design has attrac…
Tailoring Molecules for Protein Pockets: a Transformer-based Generative Solution for Structured-based Drug Design
Kehan Wu, Yingce Xia, Yang Fan +7
Structure-based drug design is drawing growing attentions in computer-aided drug discovery. Compared with the virtual screening approach where a pre-defined library of compounds ar…
Unified 2D and 3D Pre-Training of Molecular Representations
Jinhua Zhu, Yingce Xia, Lijun Wu +5
Molecular representation learning has attracted much attention recently. A molecule can be viewed as a 2D graph with nodes/atoms connected by edges/bonds, and can also be represent…
SSM-DTA: Breaking the Barriers of Data Scarcity in Drug-Target Affinity Prediction
Qizhi Pei, Lijun Wu, Jinhua Zhu +6
Accurate prediction of Drug-Target Affinity (DTA) is of vital importance in early-stage drug discovery, facilitating the identification of drugs that can effectively interact with…
A Survey on Non-Autoregressive Generation for Neural Machine Translation and Beyond
Yisheng Xiao, Lijun Wu, Junliang Guo +4
Non-autoregressive (NAR) generation, which is first proposed in neural machine translation (NMT) to speed up inference, has attracted much attention in both machine learning and na…
Dynamic Relation Discovery and Utilization in Multi-Entity Time Series Forecasting
Lin Huang, Lijun Wu, Jia Zhang +2
Time series forecasting plays a key role in a variety of domains. In a lot of real-world scenarios, there exist multiple forecasting entities (e.g. power station in the solar syste…
AF: Adaptive Focus Framework for Aerial Imagery Segmentation
Lin Huang, Qiyuan Dong, Lijun Wu +3
As a specific semantic segmentation task, aerial imagery segmentation has been widely employed in high spatial resolution (HSR) remote sensing images understanding. Besides common…