activity
20002024
most citedThe physics of epigenetics

122 citations · 358 across the 18 of their papers we have counts for

collaborators

18 papers

stat.ME2024★ 15 cited

Radius selection using kernel density estimation for the computation of nonlinear measures

Johan Medrano, Abderrahmane Kheddar, Annick Lesne +1

When nonlinear measures are estimated from sampled temporal signals with finite-length, a radius parameter must be carefully selected to avoid a poor estimation. These measures are…

q-bio.MN2023

Predicting attractors from spectral properties of stylized gene regulatory networks

Dzmitry Rumiantsau, Annick Lesne, Marc-Thorsten Hütt

How the architecture of gene regulatory networks ultimately shapes gene expression patterns is an open question, which has been approached from a multitude of angles. The dominant…

q-bio.GN2019★ 14 cited

The 3D genome shapes the regulatory code of developmental genes

Julien Mozziconacci, Mélody Merle, Annick Lesne

We revisit the notion of gene regulatory code in embryonic development in the light of recent findings about genome spatial organisation. By analogy with the genetic code, we posit…

cond-mat.soft2018★ 20 cited

Kinetic signature of cooperativity in the irreversible collapse of a polymer

Vittore F. Scolari, Guillaume Mercy, Romain Koszul +2

We investigate the kinetics of a polymer collapse due to the formation of irreversible crosslinks between its monomers. Using the contact probability as a scale-dependent or…

physics.bio-ph2015★ 122 cited

The physics of epigenetics

Ruggero Cortini, Maria Barbi, Bertrand R. Caré +4

In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only t…

q-bio.NC2014

Topological determinants of self-sustained activity in a simple model of excitable dynamics on graphs

C. Fretter, A. Lesne, C. C. Hilgetag +1

Models of simple excitable dynamics on graphs are an efficient framework for studying the interplay between network topology and dynamics. This subject is a topic of practical rele…