2 papers
q-bio.MN2019
Network Inference in Systems Biology: Recent Developments, Challenges, and Applications
Michael M. Saint-Antoine, Abhyudai Singh
One of the most interesting, difficult, and potentially useful topics in computational biology is the inference of gene regulatory networks (GRNs) from expression data. Although re…
q-bio.MN2019
Evaluating Pruning Methods in Gene Network Inference
Michael M. Saint-Antoine, Abhyudai Singh
One challenge in gene network inference is distinguishing between direct and indirect regulation. Some algorithms, including ARACNE and Phixer, approach this problem by using pruni…