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20182021
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q-bio.NC2021

The information content of brain states is explained by structural constraints on state energetics

Leon Weninger, Pragya Srivastava, Dale Zhou +6

Signal propagation along the structural connectome of the brain induces changes in the patterns of activity. These activity patterns define global brain states and contain informat…

q-bio.NC2020

Is the brain macroscopically linear? A system identification of resting state dynamics

Erfan Nozari, Maxwell A. Bertolero, Jennifer Stiso +6

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are bo…

q-bio.NC2020

Deep Neural Networks Carve the Brain at its Joints

Maxwell A. Bertolero, Dustin Moraczewski, Adam Thomas +1

How an individual's unique brain connectivity determines that individual's cognition, behavior, and risk for pathology is a fundamental question in basic and clinical neuroscience.…

q-bio.NC2019

On the nature of explanations offered by network science: A perspective from and for practicing neuroscientists

Maxwell A. Bertolero, Danielle S. Bassett

Network neuroscience represents the brain as a collection of regions and inter-regional connections. Given its ability to formalize systems-level models, network neuroscience has g…

q-bio.NC2019

The human brain's network architecture is genetically encoded by modular pleiotropy

Maxwell A. Bertolero, Ann Sizemore Blevins, Graham L. Baum +5

For much of biology, the manner in which genotype maps to phenotype remains a fundamental mystery. The few maps that are known tend to show modular pleiotropy: sets of phenotypes a…

q-bio.NC2019

Multiscale and multimodal network dynamics underpinning working memory

Andrew C. Murphy, Maxwell A. Bertolero, Lia Papadopoulos +2

Working memory (WM) allows information to be stored and manipulated over short time scales. Performance on WM tasks is thought to be supported by the frontoparietal system (FPS), t…