activity
20172023
most citedBeating the reaction limits of biosensor sensitivity with dynamic tracking of single binding events

55 citations · 115 across the 6 of their papers we have counts for

collaborators

7 papers

physics.optics2023

Bond-Selective Full-Field Optical Coherence Tomography

Haonan Zong, Celalettin Yurdakul, Jian Zhao +4

Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only vis…

physics.optics2022★ 2 cited

A spatially uniform illumination source for widefield multi-spectral optical microscopy

Iris Celebi, Mete Aslan, M. Selim Unlu

Illumination uniformity is a critical parameter for excitation and data extraction quality in widefield biological imaging applications. However, typical imaging systems suffer fro…

physics.optics2022★ 3 cited

Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy

Qing Xia, Zhongyue Guo, Haonan Zong +6

Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not…

physics.optics2021

Background-Suppressed High-Throughput Mid-Infrared Photothermal Microscopy via Pupil Engineering

Haonan Zong, Celalettin Yurdakul, Yeran Bai +3

Mid-infrared photothermal (MIP) microscopy has been a promising label-free chemical imaging technique for functional characterization of specimens owing to its enhanced spatial res…

q-bio.BM2019★ 46 cited

Highly Sensitive and Label-free Digital Detection of Whole Cell E. coli with Interferometric Reflectance Imaging

Negin Zaraee, Fulya Ekiz kanik, Abdul Muyeed Bhuiya +6

Bacterial infectious diseases are a major threat to human health. Timely and sensitive pathogenic bacteria detection is crucial in identifying the bacterial contaminations and prev…

physics.bio-ph2018★ 55 cited

Beating the reaction limits of biosensor sensitivity with dynamic tracking of single binding events

Derin Sevenler, Jacob Trueb, M. Selim Ünlü

The clinical need for ultra-sensitive molecular analysis has motivated the development of several endpoint assay technologies capable of single molecule readout. These endpoint ass…

physics.comp-ph2017★ 9 cited

Nanoparticle Classification in Wide-field Interferometric Microscopy by Supervised Learning from Model

Oguzhan Avci, Celalettin Yurdakul, M. Selim Unlu

Interference enhanced wide-field nanoparticle imaging is a highly sensitive technique that has found numerous applications in labeled and label-free sub-diffraction-limited pathoge…