60 citations · 117 across the 7 of their papers we have counts for
4 papers · 1 filter
Recoverability of Ancestral Recombination Graph Topologies
Elizabeth Hayman, Anastasia Ignatieva, Jotun Hein
Recombination is a powerful evolutionary process that shapes the genetic diversity observed in the populations of many species. Reconstructing genealogies in the presence of recomb…
KwARG: Parsimonious reconstruction of ancestral recombination graphs with recurrent mutation
Anastasia Ignatieva, Rune B. Lyngsø, Paul A. Jenkins +1
The reconstruction of possible histories given a sample of genetic data in the presence of recombination and recurrent mutation is a challenging problem, but can provide key insigh…
A characterisation of the reconstructed birth-death process through time rescaling
Anastasia Ignatieva, Jotun Hein, Paul A. Jenkins
The dynamics of a population exhibiting exponential growth can be modelled as a birth-death process, which naturally captures the stochastic variation in population size over time.…
A generative angular model of protein structure evolution
Michael Golden, Eduardo García-Portugués, Michael Sørensen +3
Recently described stochastic models of protein evolution have demonstrated that the inclusion of structural information in addition to amino acid sequences leads to a more reliabl…