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q-bio.QM2019
Joint and individual analysis of breast cancer histologic images and genomic covariates
Iain Carmichael, Benjamin C. Calhoun, Katherine A. Hoadley +8
A key challenge in modern data analysis is understanding connections between complex and differing modalities of data. For example, two of the main approaches to the study of breas…
q-bio.QM2019
A Pan-Cancer and Polygenic Bayesian Hierarchical Model for the Effect of Somatic Mutations on Survival
Sarah Samorodnitsky, Katherine A. Hoadley, Eric F. Lock
We built a novel Bayesian hierarchical survival model based on the somatic mutation profile of patients across 50 genes and 27 cancer types. The pan-cancer quality allows for the m…