195 citations · 332 across the 8 of their papers we have counts for
9 papers
A numerical approach for the dynamics of active viscoelastic surfaces
Francine Kolley-Köchel, Jan Magnus Sischka, Axel Voigt +2
The dynamics of active viscoelastic surfaces plays an important role in biological systems. One prominent example is the actin cortex, a thin bio-polymer sheet underneath the outer…
Twofold mechanosensitivity ensures actin cortex reinforcement upon peaks in mechanical tension
Valentin Ruffine, Andreas Hartmann, Michael Schlierf +1
The actin cortex is an active biopolymer network underneath the plasma membrane at the periphery of mammalian cells. It is a major regulator of cell shape through the generation of…
Pulsatory patterns in active viscoelastic fluids with distinct relaxation time scales
Eloy Merlijn de Kinkelder, Elisabeth Fischer-Friedrich, Sebastian Aland
Developing tissues need to pattern themselves in space and time. A prevalent mechanism to achieve this are pulsatile active stresses generated by the actin cytoskeleton. Active gel…
Chiral flows can induce neck formation in viscoelastic surfaces
Eloy Merlijn de Kinkelder, Elisabeth Fischer-Friedrich, Sebastian Aland
During division in animal cells, the actomyosin cortex has been found to exhibit counter-rotating cortical flows, also known as chiral flows, along the axis of division. Furthermor…
On the role of mechanosensitive binding dynamics in the pattern formation of active surfaces
M. Bonati, L. D. Wittwer, S. Aland +1
The actin cortex of an animal cell is a thin polymeric layer attached to the inner side of the plasma membrane. It plays a key role in shape regulation and pattern formation on the…
The Poisson ratio of the cellular actin cortex is frequency-dependent
Marcel Mokbel, Kamran Hosseini, Sebastian Aland +1
Cell shape changes are vital for many physiological processes such as cell proliferation, cell migration and morphogenesis. They emerge from an orchestrated interplay of active cel…
Salt-dependent rheology and surface tension of protein condensates using optical traps
Louise M. Jawerth, Mahdiye Ijavi, Martine Ruer +5
An increasing number of proteins with intrinsically disordered domains have been shown to phase separate in buffer to form liquid-like phases. These protein condensates serve as si…
Active prestress leads to an apparent stiffening of cells through geometrical effects
Elisabeth Fischer-Friedrich
Tuning of active prestress e.g. through activity of molecular motors constitutes a powerful cellular tool to adjust cellular stiffness through nonlinear material properties. Unders…
Intra- and intercellular fluctuations in Min-protein dynamics decrease with cell length
Elisabeth Fischer-Friedrich, Giovanni Meacci, Joe Lutkenhaus +2
Self-organization of proteins in space and time is of crucial importance for the functioning of cellular processes. Often, this organization takes place in the presence of strong r…