3 papers
physics.med-ph2019
Mathematical modelling of drug delivery from pH-responsive nanocontainers
G. Pontrelli, G. Toniolo, S. McGinty +3
Drug delivery systems represent a promising strategy to treat cancer and to overcome the side effects of chemotherapy. In particular, polymeric nanocontainers have attracted major…
cond-mat.soft2019
Modelling phase separation in amorphous solid dispersions
Martin Meere, Giuseppe Pontrelli, Sean McGinty
Much work has been devoted to analysing thermodynamic models for solid dispersions with a view to identifying regions in the phase diagram where amorphous phase separation or drug…
physics.flu-dyn2018
Asymptotic analysis of drug dissolution in two layers having widely differing diffusion coefficients
Michael Vynnycky, Sean McKee, Martin Meere +2
This paper is concerned with a diffusion-controlled moving-boundary problem in drug dissolution, in which the moving front passes from one medium to another for which the diffusion…