4 papers
Autocorrelated measurement processes and inference for ordinary differential equation models of biological systems
Ben Lambert, Chon Lok Lei, Martin Robinson +5
Ordinary differential equation models are used to describe dynamic processes across biology. To perform likelihood-based parameter inference on these models, it is necessary to spe…
Considering discrepancy when calibrating a mechanistic electrophysiology model
Chon Lok Lei, Sanmitra Ghosh, Dominic G. Whittaker +14
Uncertainty quantification (UQ) is a vital step in using mathematical models and simulations to take decisions. The field of cardiac simulation has begun to explore and adopt UQ me…
Probabilistic Inference on Noisy Time Series (PINTS)
Michael Clerx, Martin Robinson, Ben Lambert +4
Time series models are ubiquitous in science, arising in any situation where researchers seek to understand how a system's behaviour changes over time. A key problem in time series…
Gaussian process emulation for discontinuous response surfaces with applications for cardiac electrophysiology models
Sanmitra Ghosh, David J. Gavaghan, Gary R. Mirams
Mathematical models of biological systems are beginning to be used for safety-critical applications, where large numbers of repeated model evaluations are required to perform uncer…