2 papers
q-bio.PE2020
From Best Hits to Best Matches
Peter F. Stadler, Manuela Geiß, David Schaller +5
Many of the commonly used methods for orthology detection start from mutually most similar pairs of genes (reciprocal best hits) as an approximation for evolutionary most closely r…
q-bio.PE2019
Best Match Graphs and Reconciliation of Gene Trees with Species Trees
Manuela Geiß, Marcos E. González, Alitzel López Sánchez +4
A wide variety of problems in computational biology, most notably the assessment of orthology, are solved with the help of reciprocal best matches. Using an evolutionary definition…