activity
20172021
most citedCancer phase I trial design using drug combinations when a fraction of dose limiting toxicities is attributable to one or more agents

22 citations · 27 across the 4 of their papers we have counts for

collaborators

5 papers

stat.ME2021

Improving Bayesian estimation of Vaccine Efficacy

Mauro Gasparini

A full Bayesian approach to the estimation of Vaccine Efficacy is presented, which is an improvement over the currently used exact method conditional on the total number of cases.…

stat.ME2020

On the definition of a concentration function relevant to the ROC curve

Mauro Gasparini, Lidia Sacchetto

This is a reader's reaction to a recent paper by E. Schechtman and G. Schechtman (Metron, 2019) about the correct definition of a concentration function for the diagnostic, i.e. su…

stat.ME2018★ 3 cited

Proper likelihood ratio based ROC curves for general binary classification problems

Lidia Sacchetto, Mauro Gasparini

Everybody writes that ROC curves, a very common tool in binary classification problems, should be optimal, and in particular concave, non-decreasing and above the 45-degree line. E…

stat.ME2017★ 22 cited

Cancer phase I trial design using drug combinations when a fraction of dose limiting toxicities is attributable to one or more agents

Jose L. Jimenez, Mourad Tighiouart, Mauro Gasparini

Drug combination trials are increasingly common nowadays in clinical research. However, very few methods have been developed to consider toxicity attributions in the dose escalatio…

math.ST2017★ 2 cited

Loss Functions in Restricted Parameter Spaces and Their Bayesian Applications

Pavel Mozgunov, Thomas Jaki, Mauro Gasparini

Squared error loss remains the most commonly used loss function for constructing a Bayes estimator of the parameter of interest. However, it can lead to sub-optimal solutions when…