39 citations · 116 across the 10 of their papers we have counts for
3 papers · 1 filter
Current MD forcefields fail to capture key features of protein structure and fluctuations: A case study of cyclophilin A and T4 lysozyme
Zhe Mei, Alex T. Grigas, John D. Treado +6
Globular proteins undergo thermal fluctuations in solution, while maintaining an overall well-defined folded structure. In particular, studies have shown that the core structure of…
Bridging particle deformability and collective response in soft solids
John D. Treado, Dong Wang, Arman Boromand +3
Soft, amorphous solids such as tissues, foams, and emulsions are composed of deformable particles. However, the effect of single-particle deformability on the collective behavior o…
Using physical features of protein core packing to distinguish real proteins from decoys
Alex T. Grigas, Zhe Mei, John D. Treado +3
The ability to consistently distinguish real protein structures from computationally generated model decoys is not yet a solved problem. One route to distinguish real protein struc…