3 citations · 3 across the 2 of their papers we have counts for
3 papers
Design of Trials with Composite Endpoints with the R Package CompAREdesign
Jordi Cortés Martinez, Marta Bofill Roig, Guadalupe Gómez Melis
Composite endpoints are widely used as primary endpoints in clinical trials. Designing trials with time-to-event endpoints can be particularly challenging because the proportional…
Decision tool and Sample Size Calculator for Composite Endpoints
Marta Bofill Roig, Jordi Cortés Martínez, Guadalupe Gómez Melis
Summary points: - This article considers the combination of two binary or two time-to-event endpoints to form the primary composite endpoint for leading a trial. - It discusses the…
Non-constant hazard ratios in randomized controlled trials with composite endpoints
Jordi Cortés Martínez, Moisès Gómez Mateu, KyungMann Kim +1
The hazard ratio is routinely used as a summary measure to assess the treatment effect in clinical trials with time-to-event endpoints. It is frequently assumed as constant over ti…