128 citations · 990 across the 51 of their papers we have counts for
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Optimized numerical solutions of SIRDVW multiage model controlling SARS-CoV-2 vaccine roll out: an application to the Italian scenario
Giovanni Ziarelli, Luca Dede', Nicola Parolini +2
In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive polit…
Fast and robust parameter estimation with uncertainty quantification for the cardiac function
Matteo Salvador, Francesco Regazzoni, Luca Dede' +1
Parameter estimation and uncertainty quantification are crucial in computational cardiology, as they enable the construction of digital twins that faithfully replicate the behavior…
Numerical Modelling of the Brain Poromechanics by High-Order Discontinuous Galerkin Methods
Mattia Corti, Paola F. Antonietti, Luca Dede' +1
We introduce and analyze a discontinuous Galerkin method for the numerical modelling of the equations of Multiple-Network Poroelastic Theory (MPET) in the dynamic formulation. The…
Modeling isovolumetric phases in cardiac flows by an Augmented Resistive Immersed Implicit Surface Method
Alberto Zingaro, Michele Bucelli, Ivan Fumagalli +2
A major challenge in the computational fluid dynamics modeling of the heart function is the simulation of isovolumetric phases when the hemodynamics problem is driven by a prescrib…
A mathematical model that integrates cardiac electrophysiology, mechanics and fluid dynamics: application to the human left heart
Michele Bucelli, Alberto Zingaro, Pasquale Claudio Africa +3
We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and in…
A comprehensive and biophysically detailed computational model of the whole human heart electromechanics
Marco Fedele, Roberto Piersanti, Francesco Regazzoni +6
While ventricular electromechanics is extensively studied, four-chamber heart models have only been addressed recently; most of these works however neglect atrial contraction. Inde…
A matrix-free high-order solver for the numerical solution of cardiac electrophysiology
Pasquale Claudio Africa, Matteo Salvador, Paola Gervasio +2
We propose a matrix-free solver for the numerical solution of the cardiac electrophysiology model consisting of the monodomain nonlinear reaction-diffusion equation coupled with a…
Impact of Atrial Fibrillation on Left Atrium Haemodynamics: A Computational Fluid Dynamics Study
Mattia Corti, Alberto Zingaro, Luca Dede' +1
We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-s…
An open tool based on lifex for myofibers generation in cardiac computational models
Pasquale C. Africa, Roberto Piersanti, Marco Fedele +2
Modeling the whole cardiac function involves the solution of several complex multi-physics and multi-scale models that are highly computationally demanding, which call for simpler…