activity
20202025
most citedCBCT-Based Synthetic CT Image Generation Using Conditional Denoising Diffusion Probabilistic Model

117 citations · 179 across the 22 of their papers we have counts for

collaborators

24 papers

physics.med-ph2025

Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets

Keyur D. Shah, Ibrahim Chamseddine, Xiaohan Yuan +8

Purpose: To identify a clinically interpretable subset of survival-relevant features in HN cancer using Bayesian Network (BN) and evaluate its prognostic and causal utility. Method…

cs.CV2025★ 6 cited

A Physics-Informed Deep Learning Model for MRI Brain Motion Correction

Mojtaba Safari, Shansong Wang, Zach Eidex +4

Background: MRI is crucial for brain imaging but is highly susceptible to motion artifacts due to long acquisition times. This study introduces PI-MoCoNet, a physics-informed motio…

cs.CV2025★ 3 cited

Advancing MRI Reconstruction: A Systematic Review of Deep Learning and Compressed Sensing Integration

Mojtaba Safari, Zach Eidex, Chih-Wei Chang +2

Magnetic resonance imaging (MRI) is a non-invasive imaging modality and provides comprehensive anatomical and functional insights into the human body. However, its long acquisition…

physics.med-ph2025

Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity

Keyur D. Shah, Chih-Wei Chang, Sibo Tian +6

Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter…

physics.med-ph2024

A Review of Artificial Intelligence in Brachytherapy

Jingchu Chen, Richard Qiu, Tonghe Wang +2

Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine l…

eess.IV2024

T1-contrast Enhanced MRI Generation from Multi-parametric MRI for Glioma Patients with Latent Tumor Conditioning

Zach Eidex, Mojtaba Safari, Richard L. J. Qiu +4

Objective: Gadolinium-based contrast agents (GBCAs) are commonly used in MRI scans of patients with gliomas to enhance brain tumor characterization using T1-weighted (T1W) MRI. How…

physics.med-ph2024

Optimization-Based Image Reconstruction Regularized with Inter-Spectral Structural Similarity for Limited-Angle Dual-Energy Cone-Beam CT

Junbo Peng, Tonghe Wang, Huiqiao Xie +6

Background: Limited-angle (LA) dual-energy (DE) cone-beam CT (CBCT) is considered as a potential solution to achieve fast and low-dose DE imaging on current CBCT scanners without h…

eess.IV2024★ 1 cited

Deep Learning Based Apparent Diffusion Coefficient Map Generation from Multi-parametric MR Images for Patients with Diffuse Gliomas

Zach Eidex, Mojtaba Safari, Jacob Wynne +6

Purpose: Apparent diffusion coefficient (ADC) maps derived from diffusion weighted (DWI) MRI provides functional measurements about the water molecules in tissues. However, DWI is…

physics.med-ph2024

Unsupervised Bayesian Generation of Synthetic CT from CBCT Using Patient-Specific Score-Based Prior

Junbo Peng, Yuan Gao, Chih-Wei Chang +7

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (…

physics.med-ph2024★ 1 cited

Adaptive Proton Therapy Using CBCT-Guided Digital Twins

Chih-Wei Chang, Zhen Tian, Richard L. J. Qiu +8

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a l…

physics.med-ph2024★ 3 cited

Fast MRI Reconstruction Using Deep Learning-based Compressed Sensing: A Systematic Review

Mojtaba Safari, Zach Eidex, Chih-Wei Chang +2

Magnetic resonance imaging (MRI) has revolutionized medical imaging, providing a non-invasive and highly detailed look into the human body. However, the long acquisition times of M…

cs.CV2024★ 2 cited

Mammo-CLIP: Leveraging Contrastive Language-Image Pre-training (CLIP) for Enhanced Breast Cancer Diagnosis with Multi-view Mammography

Xuxin Chen, Yuheng Li, Mingzhe Hu +5

Although fusion of information from multiple views of mammograms plays an important role to increase accuracy of breast cancer detection, developing multi-view mammograms-based com…

physics.med-ph2024★ 2 cited

Dual-Energy Cone-Beam CT Using Two Complementary Limited-Angle Scans with A Projection-Consistent Diffusion Model

Junbo Peng, Chih-Wei Chang, Richard L. J. Qiu +5

Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy.…

physics.med-ph2024

Assessing Bilateral Neurovascular Bundles Function with Pulsed Wave Doppler Ultrasound: Implications for Reducing Erectile Dysfunction Following Prostate Radiotherapy

Jing Wang, Xiaofeng Yang, Boran Zhou +5

This study aims to evaluate the functional status of bilateral neurovascular bundles (NVBs) using pulsed wave Doppler ultrasound in patients undergoing prostate radiotherapy (RT).…

physics.med-ph2023

Image-Domain Material Decomposition for Dual-energy CT using Unsupervised Learning with Data-fidelity Loss

Junbo Peng, Chih-Wei Chang, Huiqiao Xie +6

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise…

physics.med-ph2023

Hippocampus Substructure Segmentation Using Morphological Vision Transformer Learning

Yang Lei, Yifu Ding, Richard L. J. Qiu +6

Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniq…

cs.LG2023★ 6 cited

Understanding and Mitigating Extrapolation Failures in Physics-Informed Neural Networks

Lukas Fesser, Luca D'Amico-Wong, Richard Qiu

Physics-informed Neural Networks (PINNs) have recently gained popularity due to their effective approximation of partial differential equations (PDEs) using deep neural networks (D…

eess.IV2023★ 10 cited

Synthetic CT Generation from MRI using 3D Transformer-based Denoising Diffusion Model

Shaoyan Pan, Elham Abouei, Jacob Wynne +10

Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone…

eess.IV2023★ 1 cited

Cross-Shaped Windows Transformer with Self-supervised Pretraining for Clinically Significant Prostate Cancer Detection in Bi-parametric MRI

Yuheng Li, Jacob Wynne, Jing Wang +8

Biparametric magnetic resonance imaging (bpMRI) has demonstrated promising results in prostate cancer (PCa) detection using convolutional neural networks (CNNs). Recently, transfor…

eess.IV2023★ 18 cited

Cycle-guided Denoising Diffusion Probability Model for 3D Cross-modality MRI Synthesis

Shaoyan Pan, Chih-Wei Chang, Junbo Peng +7

This study aims to develop a novel Cycle-guided Denoising Diffusion Probability Model (CG-DDPM) for cross-modality MRI synthesis. The CG-DDPM deploys two DDPMs that condition each…

physics.med-ph2023

Deep Learning in MRI-guided Radiation Therapy: A Systematic Review

Zach Eidex, Yifu Ding, Jing Wang +5

MRI-guided radiation therapy (MRgRT) offers a precise and adaptive approach to treatment planning. Deep learning applications which augment the capabilities of MRgRT are systematic…

physics.med-ph2023★ 117 cited

CBCT-Based Synthetic CT Image Generation Using Conditional Denoising Diffusion Probabilistic Model

Junbo Peng, Richard L. J. Qiu, Jacob F Wynne +8

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, makin…

physics.med-ph2020★ 4 cited

Generative Adversarial Network for Image Synthesis

Yang Lei, Richard L. J. Qiu, Tonghe Wang +3

This chapter reviews recent developments of generative adversarial networks (GAN)-based methods for medical and biomedical image synthesis tasks. These methods are classified into…

eess.IV2020★ 5 cited

Deep Learning in Multi-organ Segmentation

Yang Lei, Yabo Fu, Tonghe Wang +4

This paper presents a review of deep learning (DL) in multi-organ segmentation. We summarized the latest DL-based methods for medical image segmentation and applications. These met…