conditional generative models 1gene expression conditioning 1molecular generation 1precision drug design 1transfer learning 1
From the 1 of 2 linked papers with an AI index.
2 papers
cs.LG2026
Gene Expression-Informed Jointly Controlled Generative Modeling for Precision Molecular Design
Hang Yuan, Chen Li, Wenjun Ma +2
The paper introduces JoPMol, a generative model that simultaneously conditions molecule generation on gene expression profiles and desired chemical properties to enable precision d…
cs.CL2025
TextOmics-Guided Diffusion for Hit-like Molecular Generation
Hang Yuan, Chen Li, Wenjun Ma +1
Hit-like molecular generation with therapeutic potential is essential for target-specific drug discovery. However, the field lacks heterogeneous data and unified frameworks for int…