119 citations · 269 across the 38 of their papers we have counts for
3 papers · 1 filter
Interpretable exact linear reductions via positivity
Gleb Pogudin, Xingjian Zhang
Kinetic models of biochemical systems used in the modern literature often contain hundreds or even thousands of variables. While these models are convenient for detailed simulation…
CLUE: Exact maximal reduction of kinetic models by constrained lumping of differential equations
Alexey Ovchinnikov, Isabel Cristina Pérez Verona, Gleb Pogudin +1
Motivation: Detailed mechanistic models of biological processes can pose significant challenges for analysis and parameter estimations due to the large number of equations used to…
The Dynamics of Canalizing Boolean Networks
Elijah Paul, Gleb Pogudin, William Qin +1
Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed tha…