activity
20182026
most citedTrajectoryNet: A Dynamic Optimal Transport Network for Modeling Cellular Dynamics

44 citations · 137 across the 20 of their papers we have counts for

collaborators

22 papers

cs.LG2026

Global Transport Couplings for Classifier-Free Guided Flows

Katarina Petrović, Zander W. Blasingame, Danyal Rehman +5

Optimal-transport couplings have been shown to reduce training variance in unconditional flow models, but their role in conditional generation remains unclear. A natural approach c…

cs.LG2023★ 6 cited

Simulation-free Schrödinger bridges via score and flow matching

Alexander Tong, Nikolay Malkin, Kilian Fatras +5

We present simulation-free score and flow matching ([SF]M), a simulation-free objective for inferring stochastic dynamics given unpaired samples drawn from arbitrary source and…

cs.CV2023★ 2 cited

Neural FIM for learning Fisher Information Metrics from point cloud data

Oluwadamilola Fasina, Guillaume Huguet, Alexander Tong +5

Although data diffusion embeddings are ubiquitous in unsupervised learning and have proven to be a viable technique for uncovering the underlying intrinsic geometry of data, diffus…

cs.LG2023

Graph Fourier MMD for Signals on Graphs

Samuel Leone, Aarthi Venkat, Guillaume Huguet +3

While numerous methods have been proposed for computing distances between probability distributions in Euclidean space, relatively little attention has been given to computing such…

cs.LG2023★ 4 cited

A Heat Diffusion Perspective on Geodesic Preserving Dimensionality Reduction

Guillaume Huguet, Alexander Tong, Edward De Brouwer +4

Diffusion-based manifold learning methods have proven useful in representation learning and dimensionality reduction of modern high dimensional, high throughput, noisy datasets. Su…

cs.LG2023★ 3 cited

DynGFN: Towards Bayesian Inference of Gene Regulatory Networks with GFlowNets

Lazar Atanackovic, Alexander Tong, Bo Wang +3

One of the grand challenges of cell biology is inferring the gene regulatory network (GRN) which describes interactions between genes and their products that control gene expressio…

cs.LG2023★ 34 cited

Improving and generalizing flow-based generative models with minibatch optimal transport

Alexander Tong, Kilian Fatras, Nikolay Malkin +5

Continuous normalizing flows (CNFs) are an attractive generative modeling technique, but they have been held back by limitations in their simulation-based maximum likelihood traini…

cs.LG2022★ 1 cited

Geodesic Sinkhorn for Fast and Accurate Optimal Transport on Manifolds

Guillaume Huguet, Alexander Tong, María Ramos Zapatero +3

Efficient computation of optimal transport distance between distributions is of growing importance in data science. Sinkhorn-based methods are currently the state-of-the-art for su…

cs.LG2022

Learnable Filters for Geometric Scattering Modules

Alexander Tong, Frederik Wenkel, Dhananjay Bhaskar +5

We propose a new graph neural network (GNN) module, based on relaxations of recently proposed geometric scattering transforms, which consist of a cascade of graph wavelet filters.…

cs.LG2022★ 19 cited

Manifold Interpolating Optimal-Transport Flows for Trajectory Inference

Guillaume Huguet, D. S. Magruder, Alexander Tong +4

We present a method called Manifold Interpolating Optimal-Transport Flow (MIOFlow) that learns stochastic, continuous population dynamics from static snapshot samples taken at spor…

cs.LG2022

Time-inhomogeneous diffusion geometry and topology

Guillaume Huguet, Alexander Tong, Bastian Rieck +5

Diffusion condensation is a dynamic process that yields a sequence of multiscale data representations that aim to encode meaningful abstractions. It has proven effective for manifo…

cs.LG2021

MURAL: An Unsupervised Random Forest-Based Embedding for Electronic Health Record Data

Michal Gerasimiuk, Dennis Shung, Alexander Tong +6

A major challenge in embedding or visualizing clinical patient data is the heterogeneity of variable types including continuous lab values, categorical diagnostic codes, as well as…

cs.LG2021★ 2 cited

Embedding Signals on Knowledge Graphs with Unbalanced Diffusion Earth Mover's Distance

Alexander Tong, Guillaume Huguet, Dennis Shung +5

In modern relational machine learning it is common to encounter large graphs that arise via interactions or similarities between observations in many domains. Further, in many case…

cs.LG2021★ 10 cited

Diffusion Earth Mover's Distance and Distribution Embeddings

Alexander Tong, Guillaume Huguet, Amine Natik +5

We propose a new fast method of measuring distances between large numbers of related high dimensional datasets called the Diffusion Earth Mover's Distance (EMD). We model the datas…

cs.LG2021★ 1 cited

Multimodal Data Visualization and Denoising with Integrated Diffusion

Manik Kuchroo, Abhinav Godavarthi, Alexander Tong +2

We propose a method called integrated diffusion for combining multimodal datasets, or data gathered via several different measurements on the same system, to create a joint data di…

cs.LG2020★ 2 cited

Data-Driven Learning of Geometric Scattering Networks

Alexander Tong, Frederik Wenkel, Kincaid MacDonald +2

We propose a new graph neural network (GNN) module, based on relaxations of recently proposed geometric scattering transforms, which consist of a cascade of graph wavelet filters.…

cs.LG2020★ 1 cited

Uncovering the Folding Landscape of RNA Secondary Structure with Deep Graph Embeddings

Egbert Castro, Andrew Benz, Alexander Tong +2

Biomolecular graph analysis has recently gained much attention in the emerging field of geometric deep learning. Here we focus on organizing biomolecular graphs in ways that expose…

stat.ML2020★ 44 cited

TrajectoryNet: A Dynamic Optimal Transport Network for Modeling Cellular Dynamics

Alexander Tong, Jessie Huang, Guy Wolf +2

It is increasingly common to encounter data from dynamic processes captured by static cross-sectional measurements over time, particularly in biomedical settings. Recent attempts t…

stat.ML2019

Understanding Graph Neural Networks with Generalized Geometric Scattering Transforms

Michael Perlmutter, Alexander Tong, Feng Gao +2

The scattering transform is a multilayered wavelet-based deep learning architecture that acts as a model of convolutional neural networks. Recently, several works have introduced g…

cs.LG2019★ 3 cited

Fixing Bias in Reconstruction-based Anomaly Detection with Lipschitz Discriminators

Alexander Tong, Guy Wolf, Smita Krishnaswamy

Anomaly detection is of great interest in fields where abnormalities need to be identified and corrected (e.g., medicine and finance). Deep learning methods for this task often rel…

cs.LG2019

Finding Archetypal Spaces Using Neural Networks

David van Dijk, Daniel Burkhardt, Matthew Amodio +3

Archetypal analysis is a data decomposition method that describes each observation in a dataset as a convex combination of "pure types" or archetypes. These archetypes represent ex…

cs.LG2018★ 5 cited

Interpretable Neuron Structuring with Graph Spectral Regularization

Alexander Tong, David van Dijk, Jay S. Stanley +6

While neural networks are powerful approximators used to classify or embed data into lower dimensional spaces, they are often regarded as black boxes with uninterpretable features.…