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20192026
most citedTechnology dictates algorithms: Recent developments in read alignment

155 citations · 168 across the 18 of their papers we have counts for

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Showing 2023Show all

5 papers · 1 filter

q-bio.GN2023

MetaTrinity: Enabling Fast Metagenomic Classification via Seed Counting and Edit Distance Approximation

Arvid E. Gollwitzer, Mohammed Alser, Joel Bergtholdt +5

Metagenomics, the study of genome sequences of diverse organisms cohabiting in a shared environment, has experienced significant advancements across various medical and biological…

q-bio.GN2023

SequenceLab: A Comprehensive Benchmark of Computational Methods for Comparing Genomic Sequences

Maximilian-David Rumpf, Mohammed Alser, Arvid E. Gollwitzer +5

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational…

q-bio.GN2023★ 2 cited

A rigorous benchmarking of methods for SARS-CoV-2 lineage abundance estimation in wastewater

Viorel Munteanu, Victor Gordeev, Michael Saldana +16

In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, l…

q-bio.GN2023★ 3 cited

SARS-CoV-2 Wastewater Genomic Surveillance: Approaches, Challenges, and Opportunities

Viorel Munteanu, Michael A. Saldana, David Dreifuss +29

During the SARS-CoV-2 pandemic, wastewater-based genomic surveillance (WWGS) emerged as an efficient viral surveillance tool that takes into account asymptomatic cases and can iden…

q-bio.GN2023

Genomic reproducibility in the bioinformatics era

Pelin Icer Baykal, Paweł P. Łabaj, Florian Markowetz +4

In biomedical research, validation of a new scientific discovery is tied to the reproducibility of its experimental results. However, in genomics, the definition and implementation…