445 citations · 739 across the 8 of their papers we have counts for
8 papers
Phen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation
Anirban Ghosh, Marko Trajkovski, Marie-paule Teulade-Fichou +2
Human telomeric G-quadruplex DNA structures are attractive anticancer drug targets, but the target's polymorphism complicates the drug design: different ligands prefer different fo…
Native Mass Spectrometry and Nucleic Acid G-Quadruplex Biophysics: Advancing Hand in Hand
Valérie Gabelica
While studying nucleic acids to reveal the weak interactions responsible for their three-dimensional structure and for their interactions with drugs, we also contributed to the fie…
Mass-Resolved Electronic Circular Dichroism Ion Spectroscopy
Steven Daly, Frederic Rosu, Valerie Gabelica
DNA and proteins are chiral: their three-dimensional structure cannot be superimposed with its mirror image. Circular dichroism spectroscopy is widely used to characterize chiral c…
Electronic Spectroscopy of Isolated DNA Polyanions
Steven Daly, Massimiliano Porrini, Frederic Rosu +1
In solution, UV-vis spectroscopy is often used to investigate structural changes in biomolecules (i.e., nucleic acids), owing to changes in the environment of their chromophores (i…
Influence of the Metals and Ligands in Dinuclear Complexes on Phosphopeptide Sequencing by Electron Transfer Dissociation Tandem Mass Spectrometry
Daiki Asakawa, Akio Miyazato, Frederic Rosu +1
Phosphorylation is one of the most important protein modifications, and electron-transfer dissociation tandem mass spectrometry (ETD-MS/MS) is a potentially useful method for the s…
Parallel G-duplex and C-duplex DNA with Uninterrupted Spines of AgI-Mediated Base Pairs
Steven M. Swasey, Frederic Rosu, Stacy M. Copp +2
Hydrogen bonding between nucleobases produces diverse DNA structural motifs, including canonical duplexes, guanine (G) quadruplexes and cytosine (C) i-motifs. Incorporating metal-m…
Optimizing Native Ion Mobility Q-TOF in Helium and Nitrogen for Very Fragile Noncovalent Interactions
Valérie Gabelica, Sandrine Livet, Frédéric Rosu
The meaningful comparison of ion mobility (IM) results and of collision cross section (CCS) values on different platforms is a prerequisite for using CCS for identification or stru…
Fundamentals of ion mobility spectrometry
Valerie Gabelica, Erik Marklund
Fundamental questions in ion mobility spectrometry have practical implications for analytical applications in general, and omics in particular, in three respects. (1) Understanding…