2 papers
q-bio.MN2020
Biophysical models of cis-regulation as interpretable neural networks
Ammar Tareen, Justin B. Kinney
The adoption of deep learning techniques in genomics has been hindered by the difficulty of mechanistically interpreting the models that these techniques produce. In recent years,…
q-bio.MN2018
Asymmetry between Activators and Deactivators in Functional Protein Networks
Ammar Tareen, Ned S. Wingreen, Ranjan Mukhopadhyay
Are "turn-on" and "turn-off" functions in protein-protein interaction networks exact opposites of each other? To answer this question, we implement a minimal model for the evolutio…