26 citations · 37 across the 4 of their papers we have counts for
4 papers
Biophysical models of cis-regulation as interpretable neural networks
Ammar Tareen, Justin B. Kinney
The adoption of deep learning techniques in genomics has been hindered by the difficulty of mechanistically interpreting the models that these techniques produce. In recent years,…
Asymmetry between Activators and Deactivators in Functional Protein Networks
Ammar Tareen, Ned S. Wingreen, Ranjan Mukhopadhyay
Are "turn-on" and "turn-off" functions in protein-protein interaction networks exact opposites of each other? To answer this question, we implement a minimal model for the evolutio…
Density estimation on small datasets
Wei-Chia Chen, Ammar Tareen, Justin B. Kinney
How might a smooth probability distribution be estimated, with accurately quantified uncertainty, from a limited amount of sampled data? Here we describe a field-theoretic approach…
Modeling Evolution of Crosstalk in Noisy Signal Transduction Networks
Ammar Tareen, Ned S. Wingreen, Ranjan Mukhopadhyay
Signal transduction networks can form highly interconnected systems within cells due to network crosstalk, the sharing of input signals between multiple downstream responses. To be…