1.6k citations · 4.7k across the 34 of their papers we have counts for
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Towards decoding the coupled decision-making of metabolism and epithelial-mesenchymal transition in cancer
Dongya Jia, Jun Hyoung Park, Harsimran Kaur +9
Cancer cells have the plasticity to adjust their metabolic phenotypes for survival and metastasis. During metastasis, a developmental program known as the epithelial-mesenchymal tr…
Understanding the principles of pattern formation driven by Notch signaling by integrating experiments and theoretical models
Federico Bocci, Jose Nelson Onuchic, Mohit Kumar Jolly
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the em…
Decoding the mechanisms underlying cell-fate decision-making during stem cell differentiation by Random Circuit Perturbation
Bin Huang, Mingyang Lu, Madeline Galbraith +3
Stem cells can precisely and robustly undergo cellular differentiation and lineage commitment, referred to as stemness. However, how the gene network underlying stemness regulation…