2 papers
q-bio.CB2020
Using single-cell entropy to describe the dynamics of reprogramming and differentiation of induced pluripotent stem cells
Yusong Ye, Zhuoqin Yang, Jinzhi Lei
Induced pluripotent stem cells (iPSCs) provide a great model to study the process of reprogramming and differentiation of stem cells. Single-cell RNA sequencing (scRNA-seq) enables…
q-bio.GN2020
DNA methylation heterogeneity induced by collaborations between enhancers
Yusong Ye, Zhuoqin Yang, Jinzhi Lei
During mammalian embryo development, reprogramming of DNA methylation plays important roles in the erasure of parental epigenetic memory and the establishment of naïve pluripogent…